5 Best Dog Digestive Enzymes: Expert Review Now

Does your furry friend sometimes struggle with digestion after a meal? Maybe you notice extra gas, loose stools, or just a general tummy upset. It’s tough watching our beloved dogs feel uncomfortable, and figuring out why can be confusing. You see bags and bottles of “dog digestive enzymes” on the shelf, promising relief, but which one is actually the best fit for your unique pup?

Choosing the right digestive supplement can feel like navigating a maze. You worry about ingredients, potency, and whether it will truly help your dog feel better. Spending money on a product that doesn’t work is frustrating, and your dog deserves real comfort.

This guide cuts through the confusion. We will break down exactly what digestive enzymes are, why they matter for your dog’s health, and how to spot the highest quality formulas. By the end, you will know how to confidently pick the perfect enzyme supplement to support happy, healthy digestion for your canine companion.

Top Dog Digestive Enzymes Recommendations

No. 1
Probiotics for Dogs and Digestive Enzymes - 170 Dog Probiotics Chews - Dog Probiotic - Anti Diarrhea, Upset Stomach & Gas Relief, Constipation, Canine Prebiotic - Pet Fiber Supplement - Gut Health
  • Promotes Digestive Health: This probiotic for dogs is specifically formulated to maintain a healthy gut in dogs of all sizes. They help combat common issues like diarrhea, constipation, and upset stomachs.
  • Advanced Probiotic & Prebiotic Formula: Each chew is packed with essential dog probiotics and digestive enzymes, along with fiber ensuring your canine companion gets the full spectrum of digestive support
  • Ease Stomach Discomfort: Our pet probiotics for dogs contain ingredients known for providing relief from gas, acid, and loose stool, helping your dog feel comfortable and happy. Dog probiotic, probiotic for dogs
  • Formulated for All Dogs: Created with every dog in mind, our probiotic chews for dogs are perfect for all ages and sizes - from playful puppies to wise seniors - so your loyal companion gets the nutrients they need at any stage of life
  • Veterinarian Developed & USA Made: Trust in the premium quality of our dog digestive support supplement, which are formulated by veterinarians and manufactured in the USA within an FDA-registered facility
No. 2
NaturVet – Digestive Enzymes - Plus Probiotics & Prebiotics – Helps Support Diet Change & A Healthy Digestive Tract – for Dogs & Cats (Soft Chews, 120 Count)
  • Digestive Enzymes for Dogs helps support diet change and a healthy digestive tract.
  • Veterinarian formulated with Alpha-Amylase, Protease, Lipase and Cellulase to help hydrolyze starches, proteins, triglycerides and break down cellulose.
  • Tasty soft chews that taste like a treat, packaged with a re-sealable jar to ensure freshness.
  • Since 1994, NaturVet has been manufacturing products to offer the superior quality of life your four-legged family members deserve
No. 3
Zesty Paws Probiotics for Dogs - Probiotics for Gut Flora, Digestive Health, Occasional Diarrhea & Bowel Support - Clinically Studied DE111 - Functional Dog Supplement Soft Chew for Pet Immune System
  • Something Yummy for a Happy Tummy! - Probiotic Bites are functional soft chew dog supplements that support gut flora and immune support for your canine companion.
  • Featuring DE111 - This chewable supplement contains DE111, which is a clinically studied Bacillus subtilis that supports gut health and immune system function for your doggy.
  • For a Healthy Gut - Fido can continue to digest with more zest! Probiotic Bites help support gut flora and normal digestive function for small, medium, and large breeds – whether an adult or senior!
  • Immune System Support - At a total of 3 billion CFU per chew, the probiotics in these Probiotic Bites provide paw-erful support for your dog's immunity.
  • Good Gut Bacteria - These chewables include pawsome probiotic strains such as Lactobacillus acidophilus, L. plantarum, L. brevis, L. fermentum, and Lactococcus lactis.
No. 4
NaturVet – Digestive Enzymes for Dogs - Plus Probiotics & Prebiotics | Helps Support Diet Change & A Healthy Digestive Tract | for Dogs & Cats | 4 oz Powder
  • Helps support a healthy digestive tract
  • A concentrated powder enzyme blend derived from vegetable sources
  • Probiotics help enhance normal digestion
  • Ideal for use when changing diet, after deworming or after illness
  • 4 oz
No. 5
Pan-tenex | 10x Digestive Enzymes for Dogs - 8.8 Ounces (250 Grams)
  • Highest Potency Available – 10x Porcine Pancreatic Enzyme Powder
  • Maximum Enzyme Levels To Support Digestion Of Fats, Proteins & Carbohydrates
  • Contains Lipase, Amylase & Protease Digestive Enzymes For Nutrient Absorption
  • Acetone-Free | Dust-Free | Low-Odor Formulation
  • Dosed Per Meal, Not Per Cup Of Food | Use Less & Save More
No. 6
NaturVet – Digestive Enzymes - Plus Probiotics & Prebiotics – Helps Support Diet Change & A Healthy Digestive Tract – for Dogs & Cats – 1 lb Powder
  • Forall dogs
  • Can also be used for cats
  • Tastypowder formula
  • Helps to maintain intestinal tract health
  • Aids in digestion
No. 7
Purina Pro Plan Veterinary Supplements FortiFlora Daily Probiotics for Dogs, Helps Digestive Gut Health and Diarrhea - 30 ct. Box
  • Number one probiotic supplement recommended by veterinarians (Kantar Veterinary Tracker, 2020)
  • Probiotic supplement for the dietary management of puppies and adult dogs with diarrhea
  • Contains a probiotic for dogs proven to promote intestinal health and balance
  • Promotes a strong immune system and contains antioxidants for dogs
  • Easy-to-feed dog supplement powder
No. 8
Wholistic Pet Organics Probiotics for Dogs with Digestive Enzymes & Prebiotic Fiber - 2 Oz - Daily Cat & Dog Probiotics for Digestive Health, Anti Diarrhea & Gut Support - Cat Probiotic - 57 Scoops
  • Powerful Dog Probiotic Formula: Formulated to provide high-quality dog probiotics and digestive enzymes to support gut health and digestion. This probiotic for dogs helps balance intestinal flora, improve digestion, and promote overall well-being, making it an ideal supplement for maintaining a healthy digestive system.
  • Multi-Purpose for Cats & Dogs: A comprehensive probiotic supplement suitable for both dogs and cats, addressing digestive issues and supporting overall health. This probiotic for cats and dogs helps with gastrointestinal balance, promoting better digestion and immune support for pets of all sizes, including pet probiotics for dogs.
  • Prebiotics for Dogs & Cats: Includes prebiotics to complement probiotics, ensuring a healthy gut and improved digestion for both dogs and cats. These prebiotics work together with probiotics for cats and dogs, helping to nourish beneficial gut bacteria and enhance digestion, reducing discomfort and promoting a balanced digestive system.
  • Organic Digestive Enzymes: Features natural digestive enzymes with probiotics and prebiotics for dogs, enhancing digestion and reducing food-related issues. This combination supports gut health in both dogs and cats, making it an excellent choice for pet owners looking to improve their pet’s digestive function, including probiotic for cats.
  • For Homemade Dog Food: Works as a perfect dog food supplement for homemade dog food, ensuring complete nutrition with essential enzymes and probiotics. This probiotic for dogs helps dogs digest homemade meals more effectively, ensuring optimal nutrient absorption and promoting a healthy gut. It can also be beneficial for cats, such as cat probiotics for indoor cats.

The Ultimate Buying Guide for Dog Digestive Enzymes

Dog digestive enzymes are helpful supplements. They assist your dog’s body in breaking down food. This helps unlock more nutrients. If your dog struggles with digestion, this guide can help you choose the best product.

Key Features to Look For

When shopping, look closely at the label. Certain features make a supplement better than others.

1. Enzyme Variety and Strength
  • Broad Spectrum: Good supplements include several types of enzymes. Look for amylase (breaks down carbs), lipase (breaks down fats), and protease (breaks down protein). A wider range helps digest all parts of the meal.
  • Activity Units (Activity Levels): Enzymes are measured by how much they can do. Check for units like USP or FCC. Higher numbers often mean the product is more potent.
2. Source and Purity
  • Natural Sourcing: Many high-quality enzymes come from natural sources like pineapple (bromelain) or papaya (papain). Plant-based enzymes are often preferred.
  • No Unnecessary Fillers: Avoid products packed with artificial colors, flavors, or cheap fillers like cornstarch or soy. These can sometimes upset sensitive stomachs.
3. Delivery Method
  • Capsule vs. Powder: Powders mix easily into wet food. Capsules are convenient for exact dosing. Choose the form your dog accepts best.

Important Materials and Ingredients

The materials inside the bottle matter most. Good ingredients work better and are safer.

Essential Enzymes
  • Lipase: Crucial for dogs eating fatty diets or struggling with greasy stools.
  • Protease: Helps absorb amino acids from meat and other proteins.
  • Amylase: Necessary for breaking down starches found in kibble or vegetables.
Supporting Ingredients
  • Prebiotics/Probiotics: Some formulas include these beneficial bacteria (probiotics) or the food for the bacteria (prebiotics). This offers a double benefit for gut health.

Factors That Improve or Reduce Quality

The quality of the manufacturing process significantly impacts how well the enzymes work.

Factors That Improve Quality
  • Enteric Coating: Stomach acid destroys many enzymes before they reach the small intestine where they are needed. Some premium products have an enteric coating. This coating protects the enzymes until they dissolve in the intestines.
  • Guaranteed Potency: A trustworthy company guarantees that the enzyme level listed on the label is still present when the product expires, not just when it is bottled.
Factors That Reduce Quality
  • Heat Exposure: Enzymes are fragile proteins. If the product has been exposed to high heat during storage or manufacturing, the enzymes can become damaged and useless.
  • Short Shelf Life: If the product lacks good stabilization methods, its power fades quickly.

User Experience and Use Cases

When should you give your dog these enzymes? They serve several common purposes.

Common Use Cases
  • Older Dogs: As dogs age, their natural enzyme production often slows down. Supplements help them get the most nutrition from their food.
  • Sensitive Stomachs: Dogs with chronic gas, bloating, or loose stools often see improvement.
  • Diet Changes: When switching to a raw diet or a new brand of food, enzymes help the gut adjust smoothly.
  • Food Allergies: Enzymes can sometimes help break down proteins that might otherwise trigger an allergic reaction.
Giving the Supplement

Always follow the dosage recommended by your veterinarian or the product label. Most experts suggest mixing the enzyme powder or opening the capsule directly onto your dog’s food right before feeding. Do not mix it too far ahead of time, as the enzymes will start working immediately.


10 Frequently Asked Questions (FAQ) About Dog Digestive Enzymes

Q: What are digestive enzymes for dogs?

A: They are natural substances that help break down fats, proteins, and carbohydrates in your dog’s meal. This makes nutrients easier for the body to absorb.

Q: How quickly will I see results?

A: Some owners notice softer stools or less gas within a few days. For chronic issues, it might take two to four weeks to see a clear, lasting improvement.

Q: Can I give my dog human digestive enzymes?

A: It is safer to use enzymes made specifically for dogs. Human products might have different strengths or include ingredients that are not safe for canines.

Q: Should I give enzymes with every meal?

A: Yes, for best results, most veterinarians recommend giving the recommended dose with every meal your dog eats, especially if they have ongoing digestive issues.

Q: What happens if I give too much?

A: Generally, digestive enzymes are very safe. Giving too much might lead to loose stools, but serious side effects are rare when sticking close to the recommended dose.

Q: Do I need to refrigerate these supplements?

A: Most high-quality, shelf-stable enzyme products do not require refrigeration. Always check the specific label instructions.

Q: Are plant-based enzymes better than animal-based ones?

A: Many experts prefer plant-based enzymes because they are more stable in the stomach’s acidic environment before they reach the intestines.

Q: Will this help my dog gain weight?

A: If your dog was struggling to absorb calories due to poor digestion, yes, better absorption often leads to healthier weight gain and better overall body condition.

Q: How do I store the enzyme powder correctly?

A: Store the bottle in a cool, dark, and dry place. Keep the lid tightly sealed to prevent moisture from getting inside, which can deactivate the enzymes.

Q: Is this the same as a probiotic?

A: No. Enzymes help *break down* food. Probiotics introduce *beneficial bacteria* to balance the gut environment. They are different but often work well together.